Perineural Invasion and Micrometastasis Around Autonomic Nerves in Rectal Carcinoma.
نویسندگان
چکیده
منابع مشابه
Consensus transcriptome signature of perineural invasion in pancreatic carcinoma.
Perineural invasion, the growth of tumor cells along nerves, is a key feature of pancreatic cancer. The cardinal symptom of pancreatic cancer, abdominal pain often radiating to the back, as well as the high frequency of local tumor recurrence following resection are both attributed to the unique ability of pancreatic tumor cells to invade the neuronal system. The molecular mechanisms underlying...
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The risk factors for recurrence of head and neck cancer are classified as being of high or intermediate risk. Those of intermediate risk include multiple positive nodes without extracapsular nodal spread, perineural/vascular invasion, pT3/T4 primary tumours, and positive level IV/V nodes. However, little evidence is available to validate these intermediate risk factors. We analyzed perineural/v...
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The presence of perineural invasion in skin tumors constitutes a major risk factor for local recurrence.1-3 Perineural invasion is not a common finding in basal cell carcinomas, with an estimated incidence that, depending on the series, varies between 0.17%2 and 3.8%.4 The frequency is higher in more aggressive histological subtypes and in recurrent tumors.1,2,4,5 The patient was a 69-year-old ...
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The ability of cancer cells to invade along nerves is associated with aggressive disease and diminished patient survival rates. Perineural invasion (PNI) may be mediated by nerve secretion of glial cell line-derived neurotrophic factor (GDNF) attracting cancer cell migration through activation of cell surface Ret proto-oncogene (RET) receptors. GDNF family receptor (GFR)α1 acts as coreceptor wi...
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To investigate the distribution of lymphatic tissues and nerves in the supporting ligaments around the cervix uteri for their tomographical relationship, 9 adult female cadavers were used in this study. Following the incision of all supporting ligaments around the cervix, hematoxylin and esosin (H&E) and immunohistochemical staining of various sections of these ligaments was performed to enable...
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ژورنال
عنوان ژورنال: Nippon Daicho Komonbyo Gakkai Zasshi
سال: 1998
ISSN: 1882-9619,0047-1801
DOI: 10.3862/jcoloproctology.51.457